Thrill for Krill

krill oil

You may have heard about krill oil—or maybe you haven’t. Either way, read on for an overview of the benefits of this tiny shellfish!

What are Krill?

What are Krill?

Krill are tiny crustaceans similar to shrimp and found in oceans around the world. They feed on phytoplankton—sea-faring plants that use the sun as an energy source for photosynthesis and are responsible for producing up to 80%(1) of the world’s oxygen levels. In turn, many ocean animals (and humans) use krill as food. Krill can even digest and break down some microplastics—an ability(2) currently being pretty heavily researched.

Antarctic krill (Euphausia superba) provide food for Antarctic whales, seals, fish, and squid as well as penguins and have one of the largest biomass in the world. To protect this biomass, there exists a quota for krill harvest, designed to maintain sustainability(3).

Why Krill Oil?

Krill oil contains high levels of Omega-3 essential fatty acids and may be a good or even better alternative to fish oils as a source of this important set of nutrients.

What are Omega-3 Essential Fatty Acids and Why are They important?

What are Omega-3 Essential Fatty Acids and Why are They important?

We also hear a lot about the different kinds of fats—there are “healthy” fats and not-so-healthy fats. You may have heard the terms polyunsaturated fats (PUFA), monounsaturated fats (MUFA), and saturated fats. We are told to increase the omega-3 fats …and absolutely stay away from saturated or trans fats.

Let’s define some of the terms used:

  • Fats or fatty acids (FA) are long chains of carbon atoms linked to a specific number of hydrogen and oxygen atoms. The specific way the carbon, hydrogen, and oxygen atoms are linked defines fatty acids.
  • These FA can be saturated—and THAT means that each carbon atom is attached to another carbon atom with single bonds. FAs can also be unsaturated, meaning that at least some carbon atoms are double bonded to another carbon atom. Why is this so important? Because UNsaturated fatty acids tend to be healthier fats. They can be monounsaturated, meaning there is one (mono=1) double bond—they are then abbreviated as MonoUnsaturated Fatty Acids or MUFAs. The PolyUnsaturated Fatty Acids, or PUFAs, have more than one double bond. These MUFAs and PUFAs are thought to be the healthiest fats.
  • Hydrogenated fats or fatty acids refer to the chemical processing that adds extra hydrogen atoms to the FA, making them the less healthy, fully saturated fats. The REALLY unhealthy trans fats are a result of this chemical processing.

But what is so special about the omega-3 essential fatty acids? And what about the omega-6 and the omega-9 essential fatty acids?

More Details!

One group of FA is called the essential fatty acids (or EFA) because humans cannot make them in adequate amounts for optimal health—they must be derived from the diet. The EFAs are the omega3 FAs, the omega6 FAs, and the omega-6 FAs. The numbers 3, 6, and 9 refer to the location of the double bonds on the long carbon backbone chain.

Omega-6 EFAs

There is really nothing unhealthy about omega 6 EFAs. They are in many different foods, so it is relatively easy to get enough omega-6 EFAs. This is the main reason that most physicians or healthcare professionals don’t recommend supplemental omega-6 EFAs—most people get enough. The key thing to remember is the ratio between the omega-6 FA and the omega-3 FA. Current recommendations are to get to as close to a 1:1 ratio of omega-3 and omega-6 EFAs. Because omega-6 EFAs are easy to get from the diet, it is recommended both to increase your intake of fish (a good source of omega-3 EFA) and to supplement with omega-3 EFAs.

  • Ancient humans had a much lower rate of cancer and chronic diseases. These existed, of course, but at lower rates than we currently see. Ancient humans—those hunter-gatherers—are believed to have eaten about the same amount of omega-3 and omega-6 fats—studies indicate they ate about a 1:1 ratio(4). To compare, because both plant and animal foods contain omega-6 EFAs, in some countries, people consume 20 times more Omega-6 than Omega-3! These countries also have an increase(5) in chronic diseases. 

Omega-6 EFAs mainly serve as an energy source and as precursors to other necessary components of cells, tissues, and organs. The main omega-6 EFA is gamma-linoleic acid (GLA), which the body converts to arachidonic acid, a substance important as a pro-inflammatory substance.

  • It is important to remember that we need some pro-inflammatory substances because inflammation is part of the body’s defense mechanisms against disease. Inflammation “calls” all sorts of immune cells to come to the damaged area and repair it. As always, however—it is the balance! Too much inflammation can cause permanent damage, while too little inflammation can cause recurring infections, among other things.

Omega-9 FAs

Omega-9 FAs—well, I am sneaking those in. They aren’t technically essential fatty acids, because humans can produce them. Oleic acid—from olive oil—is the most common omega-9 FA and acts like omega-3 FAs. This is why olive oil is commonly recommended for a healthy diet.

Omega-3 EFAs

Finally! What about those omega-3 EFAs?

There are three main types of omega-3 EFAs important in human health.

  • Eicosapentaenoic acid (EPA): The main function of EPA in the human body is as a building block for a group of substances known as eicosanoids (eye-ko-se-noids) which are substances with ANTI- inflammatory(6).
  • Docosahexaenoic acid (DHA):DHA is critical in brain function(7) and especially important for the developing brain. It is also beneficial for the eyes, heart, and a successful pregnancy. 
  • Alpha-linolenic acid (ALA): This fatty acid can be converted into EPA and DHA. The process is not very efficient, though, and unless supplemented for a specific reason, it is not usually recommended. It may benefit peripheral neuropathy in diabetes and cancer patients. ALA is found in flaxseed, canola, and soybean oils.

Recommended amounts of omega-3 EFAs have not definitively been established, but many physicians and healthcare professionals recommend you take enough for at least “adequate intake,” and that amount ranges from about 500mg for infants, to 700 mg for young people (under the age of 9) and 1000 mg for anyone over the age of 9. Over the age of 50, however, a bit more—1,100 mg—is considered adequate.

Back to Krill Oil

krill oil

Krill oil is rich in omega-3 EFAs—because the phytoplankton that the krill eat are high in omega-3 EFAs. Moreover, the omega-3 EFAs in krill oil come combined with phosphate groups which increase the bioavailability(8) of the omega-3 EFAs. With the increased bioavailability of krill oil—you essentially get more “bang for the buck” and greater benefits, mg per mg.

What are some of the benefits of high levels of omega-3 EFAs found in krill oil? Krill oil(9) is:

  • Anti-inflammatory
    • As mentioned, inflammation is an important aspect of the body’s defense mechanisms against injury and infection. It is also an important part of the production of pain. It may seem like you ALWAYS want to reduce pain, but remember, pain is ALSO an indication of an injury or a disease process going on—reducing pain may be necessary at times, but without the “readout” that pain provides, we would try to carry around hot plates in our bare hands, try to walk with a broken ankle—well, you get the picture. BUT—inflammation must be tightly controlled, or it will damage cells, tissues, and organs. The best way to control inflammation may be to provide your body with all the necessary building blocks to makethe anti-inflammatory substances. And krill oil is a great source of those building blocks!
  • Weight Control
    • Some studies suggest that krill oil may be useful in some weight-loss programs. Since obesity is an inflammatory condition, this may be because of the anti-inflammatory effects of krill oil.
  • Diabetes and Glucose (Blood sugar) Tolerance
    • Krill oil appears to increase the sensitivity and response of cells to insulin. This may prove helpful to those with pre-diabetes and early diabetes.
  • Heart Health
    • Krill oil has shown promise in benefiting heart health by reducing the risk of atherosclerosis, decreasing blood lipid levels, controlling high blood pressure, and preventing dangerous clots.
  • Depression

DHA is especially important in brain, and nervous system health, and krill oil appears to have positive effects on mood and anxiety. It also has an important role in preserving cognitive health, especially as we age.

Takeaways

Krill oil is an excellent source of omega-3 EFA’s EPA and DHA. These EFAs play an important role in reducing inflammation, benefiting heart health, and cognitive and mental health, and may be important in maintaining a healthy weight and blood sugar control.

Enjoy!

Resources:

  1. Behrenfeld, M. Climate-mediated dance of the plankton. Nature Clim Change 4, 880–887 (2014). https://doi.org/10.1038/nclimate2349 https://www.nature.com/articles/nclimate2349#citeas 
  2. Dawson, A.L., Kawaguchi, S., King, C.K. et al. Turning microplastics into nanoplastics through digestive fragmentation by Antarctic krill. Nat Commun 9, 1001 (2018). https://doi.org/10.1038/s41467-018-03465-9 https://www.nature.com/articles/s41467-018-03465-9#citeas 
  3. Krill – biology, ecology and fishing”. Commission for the Conservation of Antarctic Marine Living Resources. 28 April 2015. Retrieved 1 April 2017. https://www.ccamlr.org/en/fisheries/krill-%E2%80%93-biology-ecology-and-fishing 
  4. Wall, R., et al., Fatty acids from fish: the anti-inflammatory potential of long-chain omega-3 fatty acids. Nutrition Reviews, 2010. 68(5): p. 280-289. https://pubmed.ncbi.nlm.nih.gov/20500789/ 
  5. Benatar, S.R., S. Gill, and I. Bakker, Global Health and the Global Economic Crisis. American Journal of Public Health, 2011. 101(4): p. 646-653. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3052329/ 
  6. Punia S, Sandhu KS, Siroha AK, Dhull SB. Omega 3-metabolism, absorption, bioavailability and health benefits–A review. PharmaNutrition. 2019 Dec 1;10:100162. https://www.sciencedirect.com/science/article/pii/S221343441930088X 
  7. Lacombe RS, Chouinard-Watkins R, Bazinet RP. Brain docosahexaenoic acid uptake and metabolism. Molecular Aspects of Medicine. 2018 Dec 1;64:109-34. https://www.sciencedirect.com/science/article/pii/S0098299717301358 
  8. Ulven SM, Holven KB. Comparison of bioavailability of krill oil versus fish oil and health effect. Vasc Health Risk Manag 2015;11:511-24. https://www.ncbi.nlm.nih.gov/pubmed/26357480?dopt=Abstract 
  9. Burri L, Johnsen L. Krill Products: An Overview of Animal Studies. Nutrients. 2015; 7(5):3300-3321. https://doi.org/10.3390/nu7053300 https://www.mdpi.com/2072-6643/7/5/3300#cite